解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:Objective:The current study aimed to investigate the effects of body position on the level and severity of stuttering in young adults with developmental stuttering. Methods:A total of 24 subjects (male: 17; female: 7; mean age: 24.9 ± 6.2 years) with developmental stuttering participated. The participants were asked t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1817906
更新日期:2019-08-05 00:00:00
abstract:Objective:The NOCTURNIN gene links nutrient absorption and metabolism to the circadian clock. Shift workers are at a heightened risk of overweight and of developing obesity and metabolic syndrome. This study investigates the diurnal variation of NOCTURNIN in healthy volunteers and its expression levels in rotational sh...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/7582734
更新日期:2019-07-31 00:00:00
abstract::There has been a remarkable interest in finding lipid inhibitors from natural products to replace synthetic compounds, and a variety of oriental medicinal herbs are reported to have biological activity with regard to lipid inhibition. Buginawa (Bugi) is a novel combined formula that contains twelve medicinal herbs wit...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3101987
更新日期:2019-07-30 00:00:00
abstract::Q192R and L55M polymorphism were considered to be associated with the development of multiple cancers. Nevertheless, the results of these researches were inconclusive and controversial. Therefore, we conducted a meta-analysis of all eligible case-control studies to assess the association between PON1 (Q192R and L55M) ...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2019/5897505
更新日期:2019-07-28 00:00:00
abstract:Background:To improve the efficacy of regenerative treatment for gingival recessions, the autologous platelet concentrates (APCs) combined with coronally advanced flap (CAF) have been investigated. However, few studies systematically assess the complementary effect of APCs in periodontal regeneration. The present study...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2019/2587245
更新日期:2019-07-25 00:00:00
abstract:Purpose:This study aims to compare the functional outcomes of nonunion humeral diaphyseal fractures following conservative treatment when managed surgically with either a plate or intramedullary (IM) nail fixation. Methods:This was a retrospective study of 56 patients with nonunion humeral fractures following conserva...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9107898
更新日期:2019-07-22 00:00:00
abstract:Introduction:Pulp regeneration, as a treatment for pulp necrosis, has significant advantages over root canal therapy for the preservation of living pulp. To date, research on pulp regeneration has mainly focused on the transplantation of pulp stem cells into the root canal, but there is still a lack of research on the ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/4759060
更新日期:2019-07-18 00:00:00
abstract:Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2019/2931831
更新日期:2019-07-17 00:00:00
abstract:Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/6360459
更新日期:2019-07-15 00:00:00
abstract::Music exposure is known to play a positive role in learning and memory and can be a complementary treatment for anxiety and fear. However, whether juvenile music exposure affects adult behavior is not known. Two-week-old Sprague-Dawley rats were exposed to music for 2 hours daily or to background noise (controls) for ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8740674
更新日期:2019-07-14 00:00:00
abstract:Purpose:To explore the effect of VEGF (vascular endothelial growth factor) on the vasculogenic mimicry (VM) formation of Choroidal Melanoma (CM) through PI3k signal pathway, to find novel targets for CM therapy. Methods:This research investigated the molecular mechanism of VEGF promoting VM formation of CM. First, we ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3909102
更新日期:2019-07-11 00:00:00
abstract::Objective. To evaluate the efficacy of bundle intervention on healthcare-associated (HA) methicillin-resistant Staphylococcus Aureus (MRSA) infection in the neonatal intensive care unit (NICU). Methods. In this study, 11,277 infants having undergone treatment at the NICU in Xiamen, China, from January 2014 to February...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5490413
更新日期:2019-07-10 00:00:00
abstract::Xiaoxuming decoction (XXMD), a classic traditional Chinese medicine (TCM) prescription, has been used as a therapeutic in the treatment of stroke in clinical practice for over 1200 years. However, the pharmacological mechanisms of XXMD have not yet been elucidated. The purpose of this study was to develop neuroprotect...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6847685
更新日期:2019-07-10 00:00:00
abstract::Hydrocephalus is a common neurological condition that can have traumatic ramifications and can be lethal without treatment. Nowadays, during therapy radiologists have to spend a vast amount of time assessing the volume of cerebrospinal fluid (CSF) by manual segmentation on Computed Tomography (CT) images. Further, som...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3059170
更新日期:2019-07-07 00:00:00
abstract:Objective:The exact shape of the dose-response relationship between maternal body mass index (BMI) and the risk of congenital heart defects (CHDs) in infants has not been clearly defined yet. This study aims to further clarify the relationship between maternal obesity and the risk of CHDs in infants by an overall and d...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2019/1315796
更新日期:2019-07-07 00:00:00
abstract::The expression profile of long noncoding RNA (lncRNA) in human epicardial adipose tissue (EAT) has not been widely studied. In the present study, we performed RNA sequencing to analyze the expression profiles of lncRNA and mRNA in EAT in coronary artery disease (CAD) patients with and without heart failure (HF). Our r...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3945475
更新日期:2019-07-04 00:00:00
abstract:Objective of Study:To investigate, using the FEM, the influence of different notching angles on a zirconium dioxide coping with the aim of establishing the optimal connection conditions with veneering ceramic. Materials and Methods:To calculate the stresses in the connection between zirconia coping and veneering ceram...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/7485409
更新日期:2019-07-01 00:00:00
abstract::Although studies have shown that human migration is one of the risk factors for the spread of drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA), surveillance studies examining MRSA among refugee populations in the US are lacking. This study aimed to assess the prevalence and molecular...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5739247
更新日期:2019-07-01 00:00:00
abstract:Introduction:The purpose of this study was to investigate the difference in surgical outcomes between symptomatic and asymptomatic patients with primary hyperparathyroidism (PHPT) and between patients with high serum calcium and those with normal blood calcium, as well as to explore the epidemiological trend of PHPT in...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/2150159
更新日期:2019-07-01 00:00:00
abstract:Background:Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies. Considering the recent increase in the prevalence of the family virus and its risk potential, we investigated the codon usage pattern to understand its evolutionar...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5857285
更新日期:2019-06-27 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) and lung cancer, closely related to smoking, are major lung diseases affecting millions of individuals worldwide. The generated gas mixture of smoking is proved to contain about 4,500 components such as carbon monoxide, nicotine, oxidants, fine particulate matter, and aldeh...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/2025636
更新日期:2019-06-24 00:00:00
abstract::Immunomodulatory agents have been proposed as therapeutic candidates to improve outcomes in sepsis. Transferon™, a dialyzable leukocyte extract (DLE), has been supported in Mexico as an immunomodulatory adjuvant in anti-infectious therapy. Here we present a retrospective study describing the experience of a referral p...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8980506
更新日期:2019-06-23 00:00:00
abstract:Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5046934
更新日期:2019-06-23 00:00:00
abstract::MicroRNAs are small noncoding RNAs, involved in the regulation of many cellular processes in plants. Hundreds of miRNAs have been identified in cassava by various techniques, yet these identifications were constrained by a lack of miRNA templates and the narrow range of conditions in transcriptome study. In this resea...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2019846
更新日期:2019-06-19 00:00:00
abstract::The aims of this study were to investigate the reasons of transfers from long-term care hospitals (LTCHs) to emergency departments (EDs) of university hospitals in geriatric patients and to categorize the avoidable causes of these transfers. This retrospective multicenter study involved patients aged 65 years and olde...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究
doi:10.1155/2019/7041607
更新日期:2019-06-19 00:00:00
abstract:Introduction:The aim of this research was to test, in an animal model, the nerve regeneration technique with a hypoallergenic acellular dermal matrix used to wrap the microsurgical neural suture. Materials and Methods:Two groups of rats received the cut of limb right median nerves. The regeneration technique considers...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/4750624
更新日期:2019-06-17 00:00:00
abstract:Objective:The underlying mechanisms by which cystatin C affects cardiovascular disease (CVD) are not very clear. Metabolic syndrome (MetS) is a cluster of risk factors that increase the risk of CVD. Here, we aimed to investigate the association of cystatin C with metabolic syndrome and cardiovascular outcomes in non-ST...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8541402
更新日期:2019-06-16 00:00:00
abstract::Guanosine is an important building block for supramolecular gels owing to the unique self-assembly property that results from the unique hydrogen bond acceptors and donor groups. Guanosine-derived supramolecular hydrogels have promise in the fields of drug delivery, targeted release, tissue engineering applications, e...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/6258248
更新日期:2019-06-13 00:00:00
abstract::Cancer metastasis has been demonstrated as it is the culmination of a cascade of priming steps. Increasing evidence has shown that tumor-derived molecular components (TDMCs) are known as extra cellular vesicle and nonvesicle factors and serve as versatile intercellular communication vehicles which can mediate signalin...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/9258075
更新日期:2019-06-12 00:00:00
abstract::Toll-like receptors (TLRs) play a key role in the innate immune response to numerous pathogens, including Acanthamoeba spp. The aim of this study was to determine the expression of TLR2 and TLR4 in the eyes of mice following intranasal infection with Acanthamoeba spp. in relation to the host's immunological status. Am...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1401894
更新日期:2019-06-12 00:00:00
abstract::Iron deficiency anemia has been a widespread disease. As an effective and stable iron supplement, the physiochemical properties of the polysaccharide iron complex have been widely studied. In this study, we characterized a novel polysaccharide-iron(III) complex extracted in an edible fungal species Auricularia auricul...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6416941
更新日期:2019-06-11 00:00:00
abstract:Background:A multifactorial decision support system (mDSS) is a tool designed to improve the clinical decision-making process, while using clinical inputs for an individual patient to generate case-specific advice. The study provides an overview of the literature to analyze current available mDSS focused on prostate ca...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/4961768
更新日期:2019-06-06 00:00:00
abstract::The ability of Aspergillus niger strain to reduce organic and mineral pollution as well as the toxicity of two tannery wastewaters, the unhairing effluent (UE) and the final effluent (FE), taken from a local Tunisian tannery and under nonsterile conditions, was studied. Raw effluents show alkaline pH ≥11; thus experim...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9020178
更新日期:2019-06-03 00:00:00
abstract::Beta-1,3-glucanosyltransferase (Gas1p) plays important roles in cell wall biosynthesis and morphogenesis and has been implicated in DNA damage responses and cell cycle regulation in fungi. Yeast Gas1p has also been reported to participate in endoplasmic reticulum (ER) stress responses. However, the precise roles and m...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1238581
更新日期:2019-06-02 00:00:00
abstract::Early recovery from muscular injury is crucial for elite athletes. Hyperbaric oxygen therapy (HBOT) has been reported to be beneficial in terms of accelerating cell recovery and tissue repair, which are considered to be helpful for eliminating fatigue and recovering stamina. This study was performed to evaluate the ef...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/6289380
更新日期:2019-05-29 00:00:00
abstract:Background:In vitro fertilization and embryo transfer (IVF-ET) technology has been widely used in the therapy of refractory infertility. Previous studies showed that acupuncture can effectively increase the clinical pregnancy rate of IVF-ET. However, the molecular mechanism is unknown. Materials and Methods:In this st...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/4179617
更新日期:2019-05-28 00:00:00
abstract:Background:The pathogenesis of abdominal aortic aneurysm (AAA) is characterized by atherosclerosis with chronic inflammation in the aortic wall. Montelukast is a selective cys-LT 1 receptor antagonist that can suppress atherosclerotic diseases. We evaluated the in vitro properties of montelukast and its in vivo activit...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9104680
更新日期:2019-05-27 00:00:00
abstract::Renal inflammation can result in renal injury. Uric acid (UA) is the final product of purine metabolism in humans and because of the lack of urate oxidase, UA may accumulate in tissues, including kidney, causing inflammation. Galangin was isolated from a traditional Chinese medicine plant and possesses several benefic...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3018357
更新日期:2019-05-26 00:00:00
abstract:Objective:Hepatitis B virus (HBV) causes inflammation of the liver and is the leading cause of both liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Serine protease inhibitor Kazal type 1 (SPINK1) is an acute-phase response protein that is overexpressed in liver cancer tissue. This study investigated the clinic...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9321494
更新日期:2019-05-22 00:00:00
abstract:Aim:The aim of this study was to explore the correlation of chemokine receptor CXCR3 with M2 macrophage infiltration, various clinicopathological features, and prognosis in patients diagnosed with gastric cancer (GC). Methods:Expression of CXCR3 protein and M2 macrophage was evaluated in 156 GC patients and correspond...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6832867
更新日期:2019-05-21 00:00:00